The full planning application, lodged with North Somerset Council, forms part of wider 20-year plans by St. Modwen and the HCA to redevelop the 82-hectare site with 1,250 homes.
Plans also include 60,000 square metres of employment space and retail and community facilities, which the HCA expects will create 2,000 jobs.
If the latest application is approved, St. Modwen will build 22 one- and two-bed apartments and 128 two-, three- and four-bed houses, with 30 per cent of homes affordable. There will also be car parking, public open spaces and infrastructure works.
The application follows the approval of the first phase of the Locking Parklands development, involving 100 homes, a 3,195 square metre innovation centre and a 2,024 square metre office development.
The HCA said two-thirds of the phase one housing has now been built, adding that it has invested about £6million in the first phase of development and a total of more than £12.2million in Locking Parklands since 2002.
Rupert Joseland, St. Modwen’s South West regional director, said: "We have constructed the first homes to a higher standard than required by building regulations, making each home up to 25 per cent more energy efficient than the standard newly built home".