The proposals include a mix of medium and small-sized logistics units ranging from approximately 700 square metres to 18,500 square metres across a 36.9-hectare site next to Junction 6 of the M56 motorway and close to the existing airport freight area.
The proposals also include 14.8-hectares of new landscaped areas and habitats surrounding the site.
MAG’s airport city director John Atkins said: "This scheme will create a sustainable commercial product of international significance that will provide high quality and well-connected logistics facilities with access to the global marketplace and a population of over 24m people within a two-hour drive time.
"This connectivity will create an exceptional opportunity to improve international trade, cut transit times and drive more efficient, sustainable supply chains whilst supporting the local community, increasing employment opportunities and stimulating economic activity in the North West."
The proposals form part of the 60.7-hectare Airport City scheme, unveiled by chancellor George Osborne in January, which is intended to transform the area into a global business hub.
Manchester Airport was announced as one of the coalition government’s first enterprise zones in March 2011.